BPH is not necessarily progressive. Patients may present with varying degrees of irritative symptoms or in urinary retention.
Medical Treatment for Irritative Symptoms
1. Alpha-1 blockers.
These medications, such as Hytrin, Cardura, and Flomax, relax the smooth muscle in the prostate, allowing the bladder to empty better. In addition, these medications may also lower the serum cholesterol and triglycerides. However, in some men, they may affect ejaculation by allowing retrograde ejaculation to occur.
2. Anti-androgens.
Finasteride (Proscar) is an anti-androgen that blocks the conversion of testosterone to dihydrotestosterone. The conversion to DHT is through the enzyme 5-alpha reductase and Proscar blocks this enzyme.
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